Pediatric Bone Marrow Transplantation

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Pediatric Blood and Marrow Transplantation

Kids RuleThe Division of Pediatric Blood and Marrow Transplantation at Duke is an internationally recognized program dedicated to providing outstanding care and support to pediatric patients who can be helped by transplantation therapy. The program is known to be a leader in both established techniques and research initiatives. Under the direction of Joanne Kurtzberg, M.D., the program has  performed approximately 1200 autologous and allogeneic transplants in children with cancer or genetic diseases since 1990. Using a variety of approaches the program has pioneered the use of both matched and  mismatched umbilical cord blood stem cells in patients who do not have a sibling donor, thus extending  this life-saving therapy to many more patients. The cord blood program allows us to identify unrelated  donors quickly (generally within a few weeks). We know that sometimes quick identification can be very important for patients with inborn errors of metabolism, bone marrow failure, immunodeficiency syndromes, or advanced leukemias.

The program provides transplant as a treatment option for a variety of acquired and congenital disorders of children and young adults including hematopoietic malignancies and solid tumors, inherited immune deficiency syndromes, bone marrow failure syndromes, and inherited metabolic diseases. Allogeneic and autologous bone marrow, peripheral stem cell and umbilical cord blood transplants have been performed for pediatric patients to treat these diseases.

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