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Carolinas Cord Blood Bank

  Diseases Treated

Allogeneic and autologous transplants are performed for pediatric patients with the following diseases:

  • Acute Leukemia
    • Acute Lymphoblastic Leukemia (ALL) in remission
      • Infant ALL (MLL or 11q23+)
      • T-cell ALL
      • B-precursor ALL
      • Ph+ ALL (T 9;11)
      • ALL with high risk features in first remission at diagnosis including
        T4;11, MLL, T1;19, WBC>300K
    • Acute Non-Lymphocytic Leukemia (ANLL)
    • Acute Myelogenous Leukemia (AML)
    • Secondary AML
    • Acute Undifferentiated Leukemia
    • Stem Cell Leukemia
    • Biphenotypic Leukemia

  • Chronic Leukemia
    • Chronic Myelogenous Leukemia (CML)
    • Juvenile CML (JCML) or CMML

  • Myelodysplastic Syndromes (MDS)
    • MDS
    • Monosomy 7
    • Monosomy 5

  • Lymphoma
    • Non-Hodgkin’s Lymphoma (NHL)
      • Lymphoblastic Lymphoma
      • Burkitt’s Lymphoma
      • Large Cell Lymphoma
      • Mantle Cell Lymphoma
      • Histiocytic Lymphoma
    • Hodgkin’s Disease (HD)

  • Brain Tumors
    • Medulloblastoma
    • Astrocytoma
    • Pineoblastoma
    • Retinoblastoma
    • Glioblastoma Multiforme
    • PNET
    • Rhabdoid Brain Tumors


  • Solid Tumors
    • Neuroblastoma
    • Wilm’s Tumor
    • Rhabdomyosarcoma
    • Ewing’s Sarcoma
    • Osteogenic Sarcoma
    • Retinoblastoma
    • PNET

  • Immunodeficiency Syndromes
    • Severe Combined Immunodeficiency Syndrome (SCID)
      • X-Linked SCID
      • ADA Deficiency
      • PNP Deficiency
      • Nezelof’s Syndrome
      • Zap-70 Deficiency
      • Idiopathic SCID
      • CID
      • X-Linked Lymphoproliferative Syndrome
    • Common Variable Immunodeficiency Disease (CVID)
    • Wiskott-Aldrich Syndrome (WAS)
    • Cartiledge-Hair Hypoplasia
    • Reticular Dysgenesis
    • Familial Erythrophagocytic Lymphohistiocytosis (FEL)

  • Histiocytic Syndromes
    • Histiocytoisis
    • LHL
    • FEL

    • White Blood Cell Disorders
      • Leukocyte Adhesion Deficiency (LAD)
      • (LFA-1 Deficiency, CD11/18)
      • Chronic Granulomatous Disease (CGD)
      • Chediak Higashi Syndrome
      • Kostmann’s Syndrome (Congenital Neutropenia)

    • Red Blood Cell Disorders
      • Sickle Cell Anemia
      • Thalassemia Major
      • Blackfan-Diamond Anemia
      • (Congenital Pure Red Cell Aplasia)
      • Sideroblastic Anemia
      • Other transfusion-dependent anemias

    • Platelet Disorders
      • Amegakaryocytic Thrombocytopenia (AMT)
      • Thrombocytopenia with Absent Radii (TAR) Syndrome

    • Bone Marrow Failure Disorders
      • Fanconi Anemia
      • Congenital Aplastic Anemia
      • Dyskeratosis Congenita
      • Acquired Severe Aplastic Anemia
      • Paroxsysmal Nocturnal Hemoglobinuria (PNH)
      • Amegakaryocytic Thrombocytopenia (AMT)

    • Inborn Errors of Metabolism
      • Mucopolysaccharidoses
        • Hurler Syndrome (MPI)
        • Hurler-Scheie
        • San Filippo Syndrome
        • Maroteaux-Lamy Syndrome (MP VI)
           
      • Leukodystrophies
        • Adrenoleukodystrophy (ALD)
        • Krabbe Disease (Globoid Leukodystrophy)
        • Metachromatic Leukodystrophy (MLD)

    • Others
      • Osteopetrosis
      • Niemann-Pick Disease (Types A and B)
      • Lesch-Nyhan Syndrome
      • Hypophosphatasia
      • Gaucher Disease
      • Mannosidosis
      • Tay Sachs Disease (GM2)
      • GM1
 

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