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Sarcoma Clinical Trials

 

A Randomized, Double-Blind, Placebo-Controlled Study of a Fixed Dose of Subcutaneous Methylnaltrexone in Adults With Advanced Illness and Opioid-Induced Constipation: Efficacy, Safety, and Additional Health Outcomes

IRB #:
Study Summary

Enrollment: Any Advanced Cancer Diagnosis + Clinically significant constipation (fewer than 3 per week) + Receiving opioids, both:  on a regular schedule, not just as-needed (PRN) or rescue doses


Open-Label Extension Study to Assess the Safety of a Fixed Dose of Subcutaneous Methylnaltrexone in Subjects With Advanced Illness and Opioid-Induced Constipation

IRB #:
Study Summary

Enrollment: Any Advanced Cancer Diagnosis + Clinically significant constipation (fewer than 3 per week) + Receiving opioids, both:  on a regular schedule, not just as-needed (PRN) or rescue doses + Participation in the study above


Randomized Placebo-Controlled Trial of the Efficacy And Tolerability Of Flexibly Dosed Pregabalin (Lyrica)  In The Treatment Of Cancer-Induced Bone Pain

IRB #:
Study Summary

Enrollment: Any Solid Tumor Cancer Diagnosis with metastatisis to the bone+ patient reported worst daily pain score of > 4 out of 10 at site of metastisis.


Spirituality-sensitive care, quality of life, and satisfaction with care among Duke Oncology Inpatients and their informal caregivers

IRB #: Pro00001511
Study Summary

Enrollment: All Cancer Diagnoses