Donald P. McDonnell, Ph.D.
Recent Publications

Frigo DE,Sherk AB,Wittmann BM,Norris JD,Wang Q,Joseph JD,Toner AP,Brown M,McDonnell DP. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro.,9/1/2009, (1385-96) - Molecular endocrinology (Baltimore, Md.) Abstract [More ...] Grasfeder LL,Gaillard S,Hammes SR,Ilkayeva O,Newgard CB,Hochberg RB,Dwyer MA,Chang CY,McDonnell DP. Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha.,8/1/2009, (1171-82) - Molecular endocrinology (Baltimore, Md.) Abstract [More ...] Joseph JD,Wittmann BM,Dwyer MA,Cui H,Dye DA,McDonnell DP,Norris JD. Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists.,7/21/2009, (12178-83) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...] Norris JD,Joseph JD,Sherk AB,Juzumiene D,Turnbull PS,Rafferty SW,Cui H,Anderson E,Fan D,Dye DA,Deng X,Kazmin D,Chang CY,Willson TM,McDonnell DP. Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands.,4/24/2009, (452-60) - Chemistry & biology Abstract [More ...] Clyne CD,Chang CY,Safi R,Fuller PJ,McDonnell DP,Young MJ. Purification and characterization of recombinant human mineralocorticoid receptor.,4/10/2009, (81-5) - Molecular and cellular endocrinology Abstract [More ...] Stein RA,Gaillard S,McDonnell DP. Estrogen-related receptor alpha induces the expression of vascular endothelial growth factor in breast cancer cells.,3/1/2009, (106-12) - The Journal of steroid biochemistry and molecular biology Abstract [More ...] Wardell SE,Ilkayeva OR,Wieman HL,Frigo DE,Rathmell JC,Newgard CB,McDonnell DP. Glucose metabolism as a target of histone deacetylase inhibitors.,3/1/2009, (388-401) - Molecular endocrinology (Baltimore, Md.) Abstract [More ...] Safi R,Muramoto GG,Salter AB,Meadows S,Himburg H,Russell L,Daher P,Doan P,Leibowitz MD,Chao NJ,McDonnell DP,Chute JP. Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture.,2/1/2009, (188-201) - Molecular endocrinology (Baltimore, Md.) Abstract [More ...] Stein RA,Chang CY,Kazmin DA,Way J,Schroeder T,Wergin M,Dewhirst MW,McDonnell DP. Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer.,11/1/2008, (8805-12) - Cancer research Abstract [More ...] Sherk AB,Frigo DE,Schnackenberg CG,Bray JD,Laping NJ,Trizna W,Hammond M,Patterson JR,Thompson SK,Kazmin D,Norris JD,McDonnell DP. Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.,9/15/2008, (7475-83) - Cancer research Abstract [More ...]

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