- Author
- Vergara SV,Thiele DJ
- Title
- Ironing out a midlife crisis.
- Publication Date
- 6/26/2009
- Pages
- 1179-81
- Journal Name
- Cell
- Abstract
- There is a strong correlation between age, genomic instability, and the development of cancer. Working in yeast, Veatch et al. (2009) now propose that defects in the biogenesis of iron-sulfur clusters arising as a consequence of mitochondrial dysfunction contribute to the increase in genomic instability as cells age.
|
DUKEHEALTH.ORG
SCHOOL OF MEDICINE
DUKE UNIVERSITY
