High-Impact Journal Publications

Kurokawa M,Kornbluth S. Caspases and kinases in a death grip., , (838-54) - Cell Abstract [More ...]

Song J,Bishop BL,Li G,Grady R,Stapleton A,Abraham SN. TLR4-mediated expulsion of bacteria from infected bladder epithelial cells., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Heitman J. Microbial genetics: Love the one you're with., , (807-8) - Nature No abstract available [More ...]

Joseph JD,Wittmann BM,Dwyer MA,Cui H,Dye DA,McDonnell DP,Norris JD. Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists., , (12178-83) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Vergara SV,Thiele DJ. Ironing out a midlife crisis., , (1179-81) - Cell Abstract [More ...]

Zidar DA,Violin JD,Whalen EJ,Lefkowitz RJ. Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands., , (9649-54) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Giangreco A,Arwert EN,Rosewell IR,Snyder J,Watt FM,Stripp BR. Stem cells are dispensable for lung homeostasis but restore airways after injury., , (9286-91) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Butler G,Rasmussen MD,Lin MF,Santos MA,Sakthikumar S,Munro CA,Rheinbay E,Grabherr M,Forche A,Reedy JL,Agrafioti I,Arnaud MB,Bates S,Brown AJ,Brunke S,Costanzo MC,Fitzpatrick DA,de Groot PW,Harris D,Hoyer LL,Hube B,Klis FM,Kodira C,Lennard N,Logue ME,Martin R,Neiman AM,Nikolaou E,Quail MA,Quinn J,Santos MC,Schmitzberger FF,Sherlock G,Shah P,Silverstein KA,Skrzypek MS,Soll D,Staggs R,Stansfield I,Stumpf MP,Sudbery PE,Srikantha T,Zeng Q,Berman J,Berriman M,Heitman J,Gow NA,Lorenz MC,Birren BW,Kellis M,Cuomo CA. Evolution of pathogenicity and sexual reproduction in eight Candida genomes., , (657-62) - Nature Abstract [More ...]

Virshup DM,Forger DB. Keeping the beat in the rising heat., , (602-4) - Cell Abstract [More ...]

Caron MG,Wightman RM. "To learn, you must pay attention." Molecular insights into teachers' wisdom., , (7267-8) - Proceedings of the National Academy of Sciences of the United States of America No abstract available [More ...]

Sanz C,Rodríguez-Romero J,Idnurm A,Christie JM,Heitman J,Corrochano LM,Eslava AP. Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism., , (7095-100) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Shenoy SK,Modi AS,Shukla AK,Xiao K,Berthouze M,Ahn S,Wilkinson KD,Miller WE,Lefkowitz RJ. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2., , (6650-5) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Semighini CP,Heitman J. Dynamic duo takes down fungal villains., , (2971-2) - Proceedings of the National Academy of Sciences of the United States of America No abstract available [More ...]

Sun L,Wang H,Hu J,Han J,Matsunami H,Luo M. Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate., , (2041-6) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Nicchitta CV. Cell biology: How to combat stress., , (668-9) - Nature No abstract available [More ...]

Read TA,Fogarty MP,Markant SL,McLendon RE,Wei Z,Ellison DW,Febbo PG,Wechsler-Reya RJ. Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma., , (135-47) - Cancer cell Abstract [More ...]

Zhao C,Chen A,Jamieson CH,Fereshteh M,Abrahamsson A,Blum J,Kwon HY,Kim J,Chute JP,Rizzieri D,Munchhof M,VanArsdale T,Beachy PA,Reya T. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia., . Nature Abstract [More ...]

Masri B,Salahpour A,Didriksen M,Ghisi V,Beaulieu JM,Gainetdinov RR,Caron MG. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics., , (13656-61) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Frederick JP,Tafari AT,Wu SM,Megosh LC,Chiou ST,Irving RP,York JD. A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation., , (11605-12) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Yang ZJ,Ellis T,Markant SL,Read TA,Kessler JD,Bourboulas M,Schüller U,Machold R,Fishell G,Rowitch DH,Wainwright BJ,Wechsler-Reya RJ. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells., , (135-45) - Cancer cell Abstract [More ...]

Shukla AK,Violin JD,Whalen EJ,Gesty-Palmer D,Shenoy SK,Lefkowitz RJ. Distinct conformational changes in {beta}-arrestin report biased agonism at seven-transmembrane receptors., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Beaulieu JM,Zhang X,Rodriguiz RM,Sotnikova TD,Wetsel WC,Gainetdinov RR,Caron MG. Reply to Belmaker et al.: GSK3{beta} haploinsufficiency results in lithium-like effects in the forced-swim test., , (E24) - Proceedings of the National Academy of Sciences of the United States of America No abstract available [More ...]

McLachlan JB,Shelburne CP,Hart JP,Pizzo SV,Goyal R,Brooking-Dixon R,Staats HF,Abraham SN. Mast cell activators: a new class of highly effective vaccine adjuvants., , (536-41) - Nature medicine Abstract [More ...]

Lew DJ,Burke DJ,Dutta A. The immortal strand hypothesis: how could it work?, , (21-3) - Cell No abstract available [More ...]

Salahpour A,Ramsey AJ,Medvedev IO,Kile B,Sotnikova TD,Holmstrand E,Ghisi V,Nicholls PJ,Wong L,Murphy K,Sesack SR,Wightman RM,Gainetdinov RR,Caron MG. Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter., , (4405-10) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Lim KH,Ancrile BB,Kashatus DF,Counter CM. Tumour maintenance is mediated by eNOS., . Nature Abstract [More ...]

Dinneny JR,Benfey PN. Plant stem cell niches: standing the test of time., , (553-7) - Cell Abstract [More ...]

Beaulieu JM,Zhang X,Rodriguiz RM,Sotnikova TD,Cools MJ,Wetsel WC,Gainetdinov RR,Caron MG. Role of GSK3{beta} in behavioral abnormalities induced by serotonin deficiency., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Beaulieu JM,Marion S,Rodriguiz RM,Medvedev IO,Sotnikova TD,Ghisi V,Wetsel WC,Lefkowitz RJ,Gainetdinov RR,Caron MG. A beta-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior., , (125-36) - Cell Abstract [More ...]

Idnurm A,Walton FJ,Floyd A,Heitman J. Identification of the sex genes in an early diverged fungus., , (193-6) - Nature Abstract [More ...]

Johnson CE,Huang YY,Parrish AB,Smith MI,Vaughn AE,Zhang Q,Wright KM,Van Dyke T,Wechsler-Reya RJ,Kornbluth S,Deshmukh M. Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Forester CM,Maddox J,Louis JV,Goris J,Virshup DM. Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1., , (19867-72) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Zhao C,Blum J,Chen A,Kwon HY,Jung SH,Cook JM,Lagoo A,Reya T. Loss of beta-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo., , (528-41) - Cancer cell Abstract [More ...]

Andrews NC. Climbing through medicine's glass ceiling., , (1887-9) - The New England journal of medicine No abstract available [More ...]

Zandy NL,Playford M,Pendergast AM. Abl tyrosine kinases regulate cell cell adhesion through Rho GTPases., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Wisler JW,Dewire SM,Whalen EJ,Violin JD,Drake MT,Ahn S,Shenoy SK,Lefkowitz RJ. A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Otto JC,Kelly P,Chiou ST,York JD. Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinases., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Wu JQ,Hansen DV,Guo Y,Wang MZ,Tang W,Freel CD,Tung JJ,Jackson PK,Kornbluth S. Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Xiao K,McClatchy DB,Shukla AK,Zhao Y,Chen M,Shenoy SK,Yates JR 3rd,Lefkowitz RJ. Functional specialization of {beta}-arrestin interactions revealed by proteomic analysis., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Juntilla MM,Wofford JA,Birnbaum MJ,Rathmell JC,Koretzky GA. Akt1 and Akt2 are required for {alpha}{beta} thymocyte survival and differentiation., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Pandey UB,Nie Z,Batlevi Y,McCray BA,Ritson GP,Nedelsky NB,Schwartz SL,DiProspero NA,Knight MA,Schuldiner O,Padmanabhan R,Hild M,Berry DL,Garza D,Hubbert CC,Yao TP,Baehrecke EH,Taylor JP. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS., , (859-63) - Nature Abstract [More ...]

Virshup DM,Forger DB. After hours keeps clock researchers CRYing Overtime., , (857-9) - Cell Abstract [More ...]

Rathmell JC,Kornbluth S. Filling a GAP(DH) in Caspase-Independent Cell Death., , (861-3) - Cell Abstract [More ...]

Whalen EJ,Foster MW,Matsumoto A,Ozawa K,Violin JD,Que LG,Nelson CD,Benhar M,Keys JR,Rockman HA,Koch WJ,Daaka Y,Lefkowitz RJ,Stamler JS. Regulation of beta-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2., , (511-22) - Cell Abstract [More ...]

Philip N,Haystead TA. Characterization of a UBC13 kinase in Plasmodium falciparum., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Bishop BL,Duncan MJ,Song J,Li G,Zaas D,Abraham SN. Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells., . Nature medicine Abstract [More ...]

Wang X,Ribeiro AA,Guan Z,Abraham SN,Raetz CR. Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase., , (4136-41) - Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Fogarty MP,Emmenegger BA,Grasfeder LL,Oliver TG,Wechsler-Reya RJ. Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells., . Proceedings of the National Academy of Sciences of the United States of America Abstract [More ...]

Nelson CD,Perry SJ,Regier DS,Prescott SM,Topham MK,Lefkowitz RJ. Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins., , (663-6) - Science Abstract [More ...]

Yang ZJ,Wechsler-Reya RJ. Hit 'em where they live: targeting the cancer stem cell niche., , (3-5) - Cancer cell Abstract [More ...]