Experimental Therapeutics Research Program
High-Impact Journal Publications
O'Brien S,Moore JO,Boyd TE,Larratt LM,Skotnicki AB,Koziner B,Chanan-Khan AA,Seymour JF,Gribben J,Itri LM,Rai KR. 5-Year Survival in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia in a Randomized, Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Friedman HS,Prados MD,Wen PY,Mikkelsen T,Schiff D,Abrey LE,Yung WK,Paleologos N,Nicholas MK,Jensen R,Vredenburgh J,Huang J,Zheng M,Cloughesy T. Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Lima B,Lam GK,Xie L,Diesen DL,Villamizar N,Nienaber J,Messina E,Bowles D,Kontos CD,Hare JM,Stamler JS,Rockman HA. Endogenous S-nitrosothiols protect against myocardial injury., . Proceedings of the National Academy of Sciences of the United States of America
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Quinn JA,Jiang SX,Reardon DA,Desjardins A,Vredenburgh JJ,Rich JN,Gururangan S,Friedman AH,Bigner DD,Sampson JH,McLendon RE,Herndon JE 2nd,Walker A,Friedman HS. Phase II trial of temozolomide plus o6-benzylguanine in adults with recurrent, temozolomide-resistant malignant glioma., , (1262-7) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Yan H,Parsons DW,Jin G,McLendon R,Rasheed BA,Yuan W,Kos I,Batinic-Haberle I,Jones S,Riggins GJ,Friedman H,Friedman A,Reardon D,Herndon J,Kinzler KW,Velculescu VE,Vogelstein B,Bigner DD. IDH1 and IDH2 mutations in gliomas., , (765-73) - The New England journal of medicine
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Zhao C,Chen A,Jamieson CH,Fereshteh M,Abrahamsson A,Blum J,Kwon HY,Kim J,Chute JP,Rizzieri D,Munchhof M,VanArsdale T,Beachy PA,Reya T. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia., . Nature
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Kabbinavar FF,Hurwitz HI,Yi J,Sarkar S,Rosen O. Addition of Bevacizumab to Fluorouracil-Based First-Line Treatment of Metastatic Colorectal Cancer: Pooled Analysis of Cohorts of Older Patients From Two Randomized Clinical Trials., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Rini BI,Michaelson MD,Rosenberg JE,Bukowski RM,Sosman JA,Stadler WM,Hutson TE,Margolin K,Harmon CS,DePrimo SE,Kim ST,Chen I,George DJ. Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma., , (3743-8) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Baer MR,George SL,Caligiuri MA,Sanford BL,Bothun SM,Mrózek K,Kolitz JE,Powell BL,Moore JO,Stone RM,Anastasi J,Bloomfield CD,Larson RA. Low-Dose Interleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older With Acute Myeloid Leukemia in First Complete Remission: Cancer and Leukemia Group B Study 9720., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Puria R,Zurita-Martinez SA,Cardenas ME. Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae., , (7194-9) - Proceedings of the National Academy of Sciences of the United States of America
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Hoang JK,Hoagland LF,Coleman RE,Coan AD,Herndon JE 2nd,Patz EF Jr. Prognostic value of fluorine-18 fluorodeoxyglucose positron emission tomography imaging in patients with advanced-stage non-small-cell lung carcinoma., , (1459-64) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Johnston S,Trudeau M,Kaufman B,Boussen H,Blackwell K,Lorusso P,Lombardi DP,Ben Ahmed S,Citrin DL,Desilvio ML,Harris J,Westlund RE,Salazar V,Zaks TZ,Spector NL. Phase II Study of Predictive Biomarker Profiles for Response Targeting Human Epidermal Growth Factor Receptor 2 (HER-2) in Advanced Inflammatory Breast Cancer With Lapatinib Monotherapy., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Grothey A,Hedrick EE,Mass RD,Sarkar S,Suzuki S,Ramanathan RK,Hurwitz HI,Goldberg RM,Sargent DJ. Response-independent survival benefit in metastatic colorectal cancer: a comparative analysis of N9741 and AVF2107., , (183-9) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Sathornsumetee S,Cao Y,Marcello JE,Herndon JE 2nd,McLendon RE,Desjardins A,Friedman HS,Dewhirst MW,Vredenburgh JJ,Rich JN. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan., , (271-8) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Patz EF Jr,Campa MJ,Gottlin EB,Kusmartseva I,Guan XR,Herndon JE 2nd. Panel of serum biomarkers for the diagnosis of lung cancer., , (5578-83) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Swanson SJ,Herndon JE 2nd,D'Amico TA,Demmy TL,McKenna RJ Jr,Green MR,Sugarbaker DJ. Video-assisted thoracic surgery lobectomy: report of CALGB 39802--a prospective, multi-institution feasibility study., , (4993-7) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Armstrong AJ,Garrett-Mayer E,Ou Yang YC,Carducci MA,Tannock I,de Wit R,Eisenberger M. Prostate-specific antigen and pain surrogacy analysis in metastatic hormone-refractory prostate cancer., , (3965-70) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Friedman HS,Maxwell J. The fallacy of single-agent chemotherapy for cancer., , (3550) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology No abstract available [
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Gollob JA,Rathmell WK,Richmond TM,Marino CB,Miller EK,Grigson G,Watkins C,Gu L,Peterson BL,Wright JJ. Phase II trial of sorafenib plus interferon alfa-2b as first- or second-line therapy in patients with metastatic renal cell cancer., , (3288-95) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Kuderer NM,Dale DC,Crawford J,Lyman GH. Impact of primary prophylaxis with granulocyte colony-stimulating factor on febrile neutropenia and mortality in adult cancer patients receiving chemotherapy: a systematic review., , (3158-67) - Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Spector NL,Yarden Y,Smith B,Lyass L,Trusk P,Pry K,Hill JE,Xia W,Seger R,Bacus SS. Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells., . Proceedings of the National Academy of Sciences of the United States of America
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O'brien S,Moore JO,Boyd TE,Larratt LM,Skotnicki A,Koziner B,Chanan-Khan AA,Seymour JF,Gregory Bociek R,Pavletic S,Rai KR. Randomized Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen Sodium (Bcl-2 antisense) in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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Rizzieri DA,Koh LP,Long GD,Gasparetto C,Sullivan KM,Horwitz M,Chute J,Smith C,Gong JZ,Lagoo A,Niedzwiecki D,Dowell JM,Waters-Pick B,Liu C,Marshall D,Vredenburgh JJ,Gockerman J,Decastro C,Moore J,Chao NJ. Partially Matched, Nonmyeloablative Allogeneic Transplantation: Clinical Outcomes and Immune Reconstitution., . Journal of clinical oncology : official journal of the American Society of Clinical Oncology
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