The Preston Robert Tisch Brain Tumor Center at Duke

Clinical Trials for Adults | Genetic/Environmental Risk and Outcomes for Brain Tumors: Main Study

Primary Objective:

  • To learn about the factors that may cause brain tumors and use this information to learn how to prevent or reduce this disease in the future
  • To determine whether polymorphisms in GST genes, CYP genes, and DNA repair genes are associated with susceptibility to brain tumors in adults
  • To accomplish these goals, individuals with and without brain tumors will be study participants

Patient Eligibility:

  • Must have a confirmed diagnosis of a NEW primary brain tumor within 6 months of enrolling
  • Tumor diagnosis is a glioblastoma, astrocytoma grades 2-4, or oligodendroglioma
  • Between 18 and 80 years old
  • English speaking
  • Reside within the United States

Control Eligibility:

  • Between 18 and 90 years old
  • Reside within the United States
  • English speaking
  • Have never had brain or spinal cancer.

Typical Participation:

  • Complete a web or telephone based questionnaire on two separate occasions
  • Provide one blood or saliva sample either at Duke University Medical Center or locally and have sample shipped to Duke

Study Plan:

Participants will be presented with study information during their clinic visit, by mail or a telephone call. Written informed consent will be obtained either in person or by mail.  Once written consent is obtained, participants will be given the study materials packet. If consent is obtained during a clinic visit, computers to complete the web based questionnaire and personnel to collect the blood or saliva sample are available at the Preston Robert Tisch Brain Tumor Center at Duke.

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